University of Texas Medical Branch at Galveston researchers have discovered a key biochemical link in the process by which the Ebola Zaire virus infects cells — a critical step to finding a way to treat the deadly disease produced by the virus.

Parents expect to pass on their eye or hair color, their knobby knees or their big feet to their children through their genes. But they don't expect to pass on viruses through those same genes.

Many nursing mothers who have been hospitalized for breast abscesses are afflicted with the "superbug" methicillin-resistant Staphylococcus aureus, or MRSA, but according to new research by UT Southwestern Medical Center physicians, conservative treatment can deal with the problem.

Scientists funded by the Wellcome Trust are to examine what is preventing the H5N1 avian influenza virus from causing a human pandemic and what mutations are required to realise its deadly potential. The research could hold the key to early identification of a potential influenza pandemic, and to developing drugs and a vaccine.

In 2006, Bluetongue virus – which infects livestock – reached Northern Europe for the first time. Some people thought that the outbreak would be limited to that particular year, as winter was expected to kill off the midges that host and spread the disease, bringing the threat of infection to an end. In actuality, the disease escalated in the following year, spreading to the UK. So, how did the virus survive the winter?

Anopheles gambiae mosquito infected with GFP-expressing AgDNV. Researchers at the Johns Hopkins Bloomberg School of Public Health's Malaria Research Institute have identified a previously unknown virus that is infectious to Anopheles gambiae—the mosquito primarily responsible for transmitting malaria. According to the researchers, the discovered virus could one day be used to pass on new genetic information to An. gambiae mosquitoes as part of a strategy to control malaria, which kills over one million people worldwide each year. The study was published August 22 online in the peer-reviewed open access journal PLoS Pathogens.

Skeletonema costatum (the chain-like organism) has been found to reduce the toxicity of the red tide organism (the round cells) to both animals and other algae. It's estimated that the red tide algae, Karenia brevis, costs approximately $20 million per bloom in economic damage off the coast of Florida alone. Scientists at the Georgia Institute of Technology have found that a diatom can reduce the levels of the red tide's toxicity to animals and that the same diatom can reduce red tide's toxicity to other algae as well. If scientists can learn to use this process to reduce the toxicity of red tide, they could reduce the vast amount of economic damage done to the seafood and tourism industries. The research appears as articles in press for the Web sites of the journals Harmful Algae and the Proceedings of the Royal Society of London B.

"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. The finding, which could aid in development of new treatments for serious infections in human patients, will be reported in the August 14 issue of the journal Cell Host & Microbe.

A yellowing infected potato plant. The white sugary-looking substance is psyllid excreta. The clear whitish substance is psyllid exoskeleton. To make a discovery and get to name it is just about every scientist's dream. For one graduate student at UC Riverside that dream already has come true.

Jessica Green of the University of Oregon's Center for Ecology and Evolutionary Biology is using molecular technique to revisit the diversity of microbes around the world. Microbial biologists, including the University of Oregon's Jessica L. Green, may not have Jimmy Buffett's music from 1977 in mind, but they are changing attitudes about evolutionary diversity on Earth, from oceanic latitudes to mountainous altitudes.

Canadian researchers have shown that patients who receive early treatment for Hepatitis C virus (HCV) within the first months following an infection, develop a rapid poly-functional immune response against HCV similar to when infection is erradicted spontaneously, according to a new study published in the Journal of Virology. Therefore, early treatment can restore immune response against HCV and help eliminate the virus rapidly. This new discovery of the mechanisms of viral eradication could contribute to the development of new treatments.

Screening the entire human genome, a team headed by Yale University scientists have identified several hundred genes that impact West Nile virus infection. The findings reported Wednesday online in the journal Nature may give scientists valuable new clues about ways to intervene in a host of deadly viral infections.

Biogeoscientists show evidence of 90 billion tons of microbial organisms—expressed in terms of carbon mass—living in the deep biosphere, in a research article published online by Nature, July 20, 2008. This tonnage corresponds to about one-tenth of the amount of carbon stored globally in tropical rainforests. The authors: Kai-Uwe Hinrichs and Julius Lipp of the Center for Marine Environmental Sciences (MARUM) at University of Bremen, Germany; and Fumio Inagaki and Yuki Morono of the Kochi Institute for Core Sample Research at the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) concluded that about 87 percent of the deep biosphere consists of Archaea. This finding is in stark contrast to previous reports, which suggest that Bacteria dominate the subseafloor ecosystem. To reach this conclusion, the researchers investigated sediment cores collected from several hundred meters beneath the seafloor of the Atlantic and Pacific Oceans and the Black Sea. The cored sediments included samples that were the result of research expeditions conducted by the Integrated Ocean Drilling Program (IODP).

For millennia, humans and viruses have been locked in an evolutionary back-and-forth -- one changes to outsmart the other, prompting the second to change and outsmart the first. With retroviruses, which work by inserting themselves into their host's DNA, the evidence remains in our genes. Last year, researchers at Rockefeller University and the Aaron Diamond AIDS Research Center brought an ancient retrovirus back to life and showed it could reproduce and infect human cells. Now, the same scientists have looked at the human side of the story and found evidence that our ancestors fought back against that virus with a defense mechanism our bodies still use today.

Viruses achieve their definition of success when they can thrive without killing their host. Now, biologists Pamela Bjorkman and Zhiru Yang of the California Institute of Technology have uncovered how one such virus, prevalent in humans, evolved over time to hide from the immune system.

Scientists here have found that certain substances from bacteria living in the human intestine cause the normally harmless Candida albicans fungus to become highly infectious.

Disease-causing microbes like the food-borne bacterium Listeria monocytogenes specialize in invading and replicating inside their animal hosts' own cells, making them particularly tricky to defeat. Now, a new study led by biologists at the University of California, Berkeley, has identified a molecular alarm system in which the intracellular pathogen sends out signals that kick the immune response into gear.

A key enzyme may explain how hepatitis C infection causes fatty liver – a buildup of excess fat in the liver, which can lead to life-threatening diseases such as cirrhosis and liver cancer, report University of Pittsburgh Graduate School of Public Health and School of Medicine researchers.

Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus. The structure provides a major step forward in understanding how the deadly virus works, and may be useful in the development of potential Ebola virus vaccines, or treatments for those infected.

Scientists have discovered how bird flu adapts in patients, offering a new way to monitor the disease and prevent a pandemic, according to research published in the August issue of the Journal of General Virology. Highly pathogenic H5N1 avian influenza virus has spread through at least 45 countries in 3 continents. Despite its ability to spread, it cannot be transmitted efficiently from human to human. This indicates it is not fully adapted to its new host species, the human. However, this new research reveals mutations in the virus that may result in a pandemic.

A new study—done on a scale an order of magnitude greater than anything previously attempted in the field of malaria—has uncovered an arsenal of proteins produced by the malaria parasite that allows it to hijack and remodel human red blood cells, leaving the oxygen-carrying cells stiff and sticky. Those effects on the blood cells play a major role in the development of malaria, a disease responsible for millions of deaths every year, the researchers report in the July 11th issue of the journal Cell, a Cell Press publication.

Researchers in Cameroon, the Democratic Republic of Congo, France, Gabon, Germany, Japan, Rwanda, the United Kingdom, and the United States have found that simian foamy virus (SFV) is widespread among wild chimpanzees throughout equatorial Africa. Details are published July 4th in the open-access journal PLoS Pathogens.

Bacteria that cause pneumonic plague can evade our first-line defences, making it difficult for the body to fight infection. In fact, a signature of the plague is the lack of an inflammatory response. Now, scientists have discovered a way to protect against death following infection with plague bacteria, by using molecules that can mimic the pathogens. According to research published in the July issue of Microbiology, these molecules make antibiotics more effective and can even be used to protect against other diseases.

Strains of bacteria that are resistant to the antibiotic vancomycin grow easily in its presence (top), but are completely eliminated (bottom) when exposed to Ceftobiprole. The problem with antibiotics is that, eventually, bacteria outsmart them and become resistant. But by targeting the gene that confers such resistance, a new drug may be able to finally outwit them. Rockefeller University scientists tested the new drug, called Ceftobiprole, against some of the deadliest strains of multidrug-resistant Staphylococcus aureus (MRSA) bacteria, which are responsible for the great majority of staphylococcal infections worldwide, both in hospitals and in the community.

Thanks to salt and hot chili peppers, researchers have found a calculus-computing center that tells a roundworm to go forward toward dinner or turn to broaden the search. It's a computational mechanism, they say, that is similar to what drives hungry college students to a pizza.

Now that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.

A laser-activated antimicrobial offers hope for new treatments of bacterial infections, even those that are resistant to current drugs. Research published today in the open access journal BMC Microbiology describes the use of a dye, indocyanine green, which produces bacteria-killing chemicals when lit by a specific kind of laser light.

Recent scientific findings explain why patients with a rare immunodeficiency disorder are unusually susceptible to certain common infections. By revealing the exact molecular mechanisms involved, they also give us clues as to why some 'healthy' people are more prone to these infections than others, and suggest potential treatments.

Recent findings by medical researchers indicate that naturally occurring nanotubes may serve as tunnels that protect retroviruses and bacteria in transit from diseased to healthy cells — a fact that may explain why vaccines fare poorly against some invaders.

Research conducted by food science faculty at the University of Idaho and Washington State University indicate that a commercially available fruit and vegetable wash, when used in a food-manufacturing setting, can dramatically decrease the number of disease-causing organisms in produce-processing washwater. That could reduce by manyfold the potential for cross-contamination within the water by such "gram-negative" bacteria as Salmonella and E. coli O157:H7.