Mammalian development is a beautifully orchestrated process of cell division and differentiation during which the various cell lineages arise that form an organism. The precise nature, origin, and fate of these lineages remain a mystery in humans and in other mammals. In addition to illuminating fundamental developmental biology, mapping human cell lineages may offer insights into a range of physiological and pathological processes, such as stem cell development, congenital diseases, and childhood cancer (1).
Author: Sam Behjati